Spacious experimental and numerical investigation has been conducted by researchers to increase the ductility and energy dissipation of concentrically braced frames.One of the most widely used strategies for increasing ductility and energy dissiption, is the use of energy-absorbing systems.In this regard, the cyclic behavior of a chevron bracing fr
Canine Lafora disease is a recessively inherited, rapidly progressing neurodegenerative disease caused by the accumulation of abnormally constructed insoluble glycogen Lafora bodies in the brain and other tissues due to the loss of NHL repeat containing E3 ubiquitin protein ligase 1 (NHLRC1).Dogs have a dodecamer repeat sequence within the NHLRC1 g
Malware detection is an ever-evolving area given that the strides in the detection capabilities being matched by radical attempts to bypass the detection.As the sophistication of malware continues to increase, the demand for innovative approaches to improve detection capabilities become paramount.Machine learning/Deep learning models are being incr
We previously identified VRK3 as a specific vulnerability in DMG-H3K27M cells in a synthetic lethality screen targeting the whole kinome.The aim of the present study was to elucidate the mechanisms by which VRK3 depletion impact DMG-H3K27M cell fitness.Gene expression studies after VRK3 knockdown emphasized the inhibition of genes involved in G1/S
Organic solvent nanofiltration (OSN) has been widely applied to separate and recycle homogeneous catalysts, but the influence of ligand and solvent selection on the performance of OSN is not fully understood.Here we prepared Safety and Hazard Lighting four palladium (Pd) catalysts by combining palladium acetate with four ligands of different molecu